James R. Stubbs, Mary J. Homer, Toby Silverman, Andrew P. Cap – “The current state of the platelet supply in the US and proposed options to decrease the risk of critical shortages”

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Federal mandates may constrain platelet availability even more4,9

The safety of platelet transfusions is critical, and recent US Food and Drug Administration (FDA) mandates on bacterial risk mitigation require platelet collections to undergo proactive safety protocols, such as large volume delayed sampling or pathogen reduction. Platelet volume loss due to methods such as these may further erode the platelet supply.4,9

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